In the pharmaceutical industry, the application of defoamers is indispensable and is crucial to improving production efficiency and ensuring drug quality. Defoamers play a key role from the extraction and fermentation of raw materials to the production of preparations.
In the extraction process of pharmaceutical raw materials, especially in the extraction of Chinese medicinal materials, a large amount of foam will be generated when the active ingredients in the medicinal materials are dissolved in the solvent, which will not only affect the extraction efficiency, but also may cause the extract to overflow and cause the waste of raw materials. At this time, adding an appropriate amount of defoamer can effectively destroy the stability of the foam and make the foam burst quickly, thereby ensuring the smooth progress of the extraction process.
When fermenting and producing antibiotics, vitamins and other drugs, the metabolic activities of microorganisms will generate a large amount of foam. These foams will not only affect the loading coefficient of the fermentation tank and reduce the fermentation efficiency, but may also affect the transfer of oxygen, causing the microbial cells to die due to lack of oxygen. Therefore, adding a defoamer during the fermentation process can effectively control the generation of foam, improve the fermentation efficiency, and ensure the quality and output of the product.
In the production process of preparations, such as the preparation of tablets, capsules, oral liquids, etc., foam is also a problem that needs to be solved. Foam can affect the mixing uniformity and tableting quality of drugs, and may even cause overflow during packaging. At this time, the application of defoaming agents can effectively eliminate foam and improve the production efficiency and product quality of preparations.
In addition, defoaming agents also play an important role in the drug research and development process in the laboratory. In experiments such as drug formula screening and stability investigation, foam may interfere with experimental results and affect the accuracy of data. Therefore, adding an appropriate amount of defoaming agent to the experiment can ensure the smooth progress of the experiment and improve research and development efficiency.
In summary, defoaming agents are widely used in the pharmaceutical industry and play an irreplaceable role in improving production efficiency and ensuring drug quality. With the continuous development of the pharmaceutical industry, the application of defoaming agents will become more extensive and in-depth.